For 25 seasons, The Simpsons have only ever participated in one official crossover episode (with The Critic) But this fall, they'll meet up for the first  time with "Family Guy's" Griffins for their season premiere. The first sizzle-reel trailer for the episode debuted.

In the special hour-long episode, The Griffins become sidetracked and find themselves in Springfield, where they make fast friends with The Simpsons based on their obvious similarities.
Simpsons / Guy Will actually be the first of two crossovers for the iconic animated family - a subsequent November episode of their own series, titled "Simpsorama,"